Nefrología

The management of acute and chronic hyponatraemia

The management of acute and chronic hyponatraemia Abstract Hyponatraemia is the most common electrolyte abnormality encountered in clinical practice; despite this, the work-up and management of hyponatraemia remain suboptimal and varies among different specialist groups. The majority of data comparing hyponatraemia treatments have been observational, up until recently. The past two years have seen the […]

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Pharmacotherapy to delay the progression of diabetic kidney disease in people with type 2 diabetes: past, present and future

Pharmacotherapy to delay the progression of diabetic kidney disease in people with type 2 diabetes: past, present and future Abstract Diabetic kidney disease (DKD) is a leading cause of morbidity and mortality among people living with diabetes, and is one of the most important causes of end stage renal disease worldwide. In order to reduce […]

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Arterial-renal Syndrome in Patients with ESRD, a New Disease Paradigm

Arterial-renal Syndrome in Patients with ESRD, a New Disease Paradigm Abstract Background Patients with end-stage renal disease (ESRD) often present with an increased risk of cardiovascular disease. Conditions of compromised cardiovascular health such as atrial fibrillation (AFIB) and peripheral arterial disease (PAD) may alter biomarker levels in a way that reflects worsening ESRD. This study […]

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The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022

The Role of the Nephrologist in Management of Poisoning and Intoxication: Core Curriculum 2022 Poisoning is a common problem in the United States. Acid-base disturbances, electrolyte derangements, or acute kidney injury result from severe poisoning from toxic alcohols, salicylates, metformin, and acetaminophen. Lithium is highly sensitive to small changes in kidney function. These poisonings and […]

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Nutrition in Kidney Disease: Core Curriculum 2022

Nutrition in Kidney Disease: Core Curriculum 2022  As chronic kidney disease (CKD) progresses, the requirements and utilization of different nutrients change substantially. These changes are accompanied by multiple nutritional and metabolic abnormalities that are observed in the continuum of kidney disease. To provide optimal care to patients with CKD, it is essential to have an understanding of […]

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Potential effects and application prospect of angiotensin receptor-neprilysin inhibitor in diabetic kidney disease

Potential effects and application prospect of angiotensin receptor-neprilysin inhibitor in diabetic kidney disease Highlights • ARNI promotes natriuresis and reduces blood pressure, contributing to renoprotection in diabetic patients. • ARNI is promising for ameliorating inflammation, oxidative stress, renal dysfunction and histopathologic changes of kidney. • ARNI may improve insulin resistance and blood glucose regulation via […]

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Innovations to Increase Home Hemodialysis Utilization: The Transitional Care Unit

Innovations to Increase Home Hemodialysis Utilization: The Transitional Care Unit A large proportion of patients undergoing incident dialysis start in-center hemodialysis with suboptimal preparation and predialysis education. Transitional care units deliver a structured program by dedicated staff, with less patient-to-staff ratios than in regular in-center dialysis care, with the goals of supporting the emotional and […]

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Renal Replacement Techniques in Septic Shock

Renal Replacement Techniques in Septic Shock Abstract Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to an infection; it carries a risk for mortality, considerably exceeding that of a mere infection. Sepsis is the leading cause for acute kidney injury (AKI) and the requirement for renal replacement therapy (RRT) […]

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Comprehensive Assessment of Fluid Status by Point-of-Care Ultrasonography

Comprehensive Assessment of Fluid Status by Point-of-Care Ultrasonography The management of complex fluid and electrolyte disorders is central to the practice of nephrologists. The sensitivity of physical examination alone to determine fluid status is limited, precluding accurate clinical decision making. Point-of-care ultrasonography (POCUS) is emerging as a valuable, noninvasive, bedside diagnostic tool for objective evaluation […]

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Comparison of Ellipsys Percutaneous and Proximal Forearm Gracz-Type Surgical Arteriovenous Fistulas

Comparison of Ellipsys Percutaneous and Proximal Forearm Gracz-Type Surgical Arteriovenous Fistulas Rationale & Objective Percutaneous arteriovenous fistulas (AVF) are created by establishing a proximal forearm anastomosis and offer a safe and reliable vascular access. This study compares the Ellipsys percutaneous AVF with a proximal forearm Gracz-type surgical AVF, chosen for comparison as it is constructed […]

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