Unexplained hemorrhagic syndrome? Consider acquired hemophilia A or B

Unexplained hemorrhagic syndrome? Consider acquired hemophilia A or B Abstract There is a dire need to develop an algorithm to improve the recognition of acquired hemophilia A and B (AHA and AHB) in clinical practice. Initial and intensive care unit (ICU) management of the disorder is particular and represents a challenge for the internist/hematologist and […]

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1-hour t-piece spontaneous breathing trial vs 1-hour zero pressure support spontaneous breathing trial and reintubation at day 7

1-hour t-piece spontaneous breathing trial vs 1-hour zero pressure support spontaneous breathing trial and reintubation at day 7: A non-inferiority approach Highlights • It remains uncertain that T-piece and zero PS spontaneous breathing trials led to similar rates of successful extubation. • No patient disconnection from the ventilator can facilitate monitoring, and could prevent aerosols […]

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2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway

2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway Las pautas de práctica son recomendaciones desarrolladas sistemáticamente que ayudan al médico y al paciente a tomar decisiones sobre la atención médica. Estas recomendaciones pueden adoptarse, modificarse o rechazarse de acuerdo con las necesidades y limitaciones clínicas y no pretenden reemplazar las políticas […]

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2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain El dolor de pecho es una de las razones más comunes por las que las personas buscan atención médica. Esta guía se desarrolló para la evaluación del dolor torácico agudo o estable en entornos ambulatorios y de urgencias, haciendo hincapié en el diagnóstico de dolor […]

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Innovations to Increase Home Hemodialysis Utilization: The Transitional Care Unit

Innovations to Increase Home Hemodialysis Utilization: The Transitional Care Unit A large proportion of patients undergoing incident dialysis start in-center hemodialysis with suboptimal preparation and predialysis education. Transitional care units deliver a structured program by dedicated staff, with less patient-to-staff ratios than in regular in-center dialysis care, with the goals of supporting the emotional and […]

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Imaging Acute Stroke: From One-Size-Fit-All to Biomarkers

Imaging Acute Stroke: From One-Size-Fit-All to Biomarkers Abstract In acute stroke management, time window has been rigidly used as a guide for decades and the reperfusion treatment is only available in the first few limited hours. Recently, imaging-based selection of patients has successfully expanded the treatment window out to 16 and even 24 h in […]

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Renal Replacement Techniques in Septic Shock

Renal Replacement Techniques in Septic Shock Abstract Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to an infection; it carries a risk for mortality, considerably exceeding that of a mere infection. Sepsis is the leading cause for acute kidney injury (AKI) and the requirement for renal replacement therapy (RRT) […]

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The diagnosis of asthma. Can physiological tests of small airways function help?

The diagnosis of asthma. Can physiological tests of small airways function help? Abstract Asthma is a common, chronic, and heterogeneous disease with a global impact and substantial economic costs. It is also associated with significant mortality and morbidity and the burden of undiagnosed asthma is significant. Asthma can be difficult to diagnose as there is […]

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Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children

Non-resuscitation fluid in excess of hydration requirements is associated with higher mortality in critically ill children Abstract Background Large volumes of non-resuscitation fluids are often administered to critically ill children. We hypothesize that excess maintenance fluid is a significant contributor to non-resuscitation fluid and that non-resuscitation fluid administered beyond hydration requirements is associated with worse […]

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Antibiotics in the pipeline: a literature review (2017–2020)

Antibiotics in the pipeline: a literature review (2017–2020) Abstract Introduction Antimicrobial resistance (AMR) is an emerging global threat. It increases mortality and morbidity and strains healthcare systems. Health care professionals can counter the rising AMR by promoting antibiotic stewardship and facilitating new drug development. Even with the economic and scientific challenges, it is reassuring that […]

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