The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition Abstract Background Severe trauma represents a major global public health burden and the management of post-traumatic bleeding continues to challenge healthcare systems around the world. Post-traumatic bleeding and associated traumatic coagulopathy remain leading causes of potentially preventable multiorgan failure and death […]
2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines Resumen Apuntar La “Guía de la AHA/ACC/HFSA de 2022 para el tratamiento de la insuficiencia cardíaca” reemplaza la “Guía de la ACCF/AHA de 2013 para el tratamiento de la insuficiencia […]
2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association Antecedentes y objetivo La hemorragia intracerebral (ICH) continúa siendo una forma mortal de accidente cerebrovascular; La mortalidad a los 90 días oscila entre el 15 % y el 40 %. Debido al aumento de la edad […]
The management of acute and chronic hyponatraemia Abstract Hyponatraemia is the most common electrolyte abnormality encountered in clinical practice; despite this, the work-up and management of hyponatraemia remain suboptimal and varies among different specialist groups. The majority of data comparing hyponatraemia treatments have been observational, up until recently. The past two years have seen the […]
Current applications and limitations of European guidelines on blood pressure measurement: implications for clinical practice Abstract Hypertension is the most common cardiovascular (CV) risk factor, strongly and independently associated with an increased risk of major CV outcomes, including myocardial infarction, stroke, congestive heart failure, renal disease and death due to CV causes. Effective control of […]
EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis Introduction Patients with cirrhosis frequently acquire substantial alterations in their haemostatic system that are apparent during screening with basic tests of haemostasis (mainly international normalised ratio [INR], activated partial thromboplastin time [APTT] and platelet count). Historically, these changes were […]
Pharmacotherapy to delay the progression of diabetic kidney disease in people with type 2 diabetes: past, present and future Abstract Diabetic kidney disease (DKD) is a leading cause of morbidity and mortality among people living with diabetes, and is one of the most important causes of end stage renal disease worldwide. In order to reduce […]
Management of hypertensive emergencies: a practical approach Abstract Background: Acute increases of high blood pressure values, usually described as ‘hypertensive crises’, ‘hypertensive urgencies’ or ‘hypertensive emergencies’, are common causes of patients’ presentation to emergency departments. Owing to the lack of ad hoc randomized clinical trials, current recommendations/suggestions for treatment of these patients are not evidenced-based and, […]
SGLT-2 inhibitors for treatment of heart failure in patients with and without type 2 diabetes: A practical approach for routine clinical practice Highlights SGLT-2i are a promising class of agents for heart failure and chronic kidney disease. An algorithm is provided for prescribing SGLT-2i using a multidisciplinary approach. Tips to prevent common adverse effects with […]
Management of status epilepticus: a narrative review SummaryStatus epilepticus causes prolonged or repetitive seizures that, if left untreated, can lead to neuronal injury, severe disability, coma and death in paediatric and adult populations. While convulsive status epilepticus can be diagnosed using clinical features alone, non-convulsive status epilepticus requires confirmation by electroencephalogram. Early seizure control remains […]