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Manifesto on the overuse of SABA in the management of asthma: new approaches and new strategies

Manifesto on the overuse of SABA in the management of asthma: new approaches and new strategies Abstract The risks of overusing short-acting β2-agonists (SABA), including an increase in asthma-related deaths, are many and well known. The Global Initiative on Asthma (GINA) 2019 and 2020 updates recommend as-needed inhaled corticosteroid (ICS)/formoterol as the preferred rescue medication […]

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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021   Screening and early treatment Screening for patients with sepsis and septic shock Recommendation 1. For hospitals and health systems, we recommend using a performance improvement programme for sepsis, including sepsis screening for acutely ill, high-risk patients and standard operating procedures for treatment Strong […]

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Comprehensive Assessment of Fluid Status by Point-of-Care Ultrasonography

Comprehensive Assessment of Fluid Status by Point-of-Care Ultrasonography The management of complex fluid and electrolyte disorders is central to the practice of nephrologists. The sensitivity of physical examination alone to determine fluid status is limited, precluding accurate clinical decision making. Point-of-care ultrasonography (POCUS) is emerging as a valuable, noninvasive, bedside diagnostic tool for objective evaluation […]

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The SIC protocol: A seven-step strategy to minimize complications potentially related to the insertion of centrally inserted central catheters

The SIC protocol: A seven-step strategy to minimize complications potentially related to the insertion of centrally inserted central catheters Abstract Insertion of central venous catheters in the cervico-thoracic area is potentially associated with the risk of immediate/early untoward events, some of them negligible (repeated punctures), some relevant (accidental arterial puncture), and some severe (pneumothorax). Furthermore, […]

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Comparison of Ellipsys Percutaneous and Proximal Forearm Gracz-Type Surgical Arteriovenous Fistulas

Comparison of Ellipsys Percutaneous and Proximal Forearm Gracz-Type Surgical Arteriovenous Fistulas Rationale & Objective Percutaneous arteriovenous fistulas (AVF) are created by establishing a proximal forearm anastomosis and offer a safe and reliable vascular access. This study compares the Ellipsys percutaneous AVF with a proximal forearm Gracz-type surgical AVF, chosen for comparison as it is constructed […]

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KDIGO 2021 CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF GLOMERULAR DISEASES

KDIGO 2021 CLINICAL PRACTICE GUIDELINE FOR THEMANAGEMENT OF GLOMERULAR DISEASES KDIGO se complace en anunciar la publicación de la Guía de práctica clínica 2021 para el manejo de enfermedades glomerulares. La guía ya está disponible en línea y se publicará en la edición de octubre de Supplements to Kidney International con un resumen ejecutivo en las páginas principales […]

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Efficacy of pinaverium bromide in the treatment of irritable bowel syndrome: a systematic review and meta-analysis

Efficacy of pinaverium bromide in the treatment of irritable bowel syndrome: a systematic review and meta-analysis Abstract Background: Spasmolytic agents are an attractive first line treatment option for irritable bowel syndrome (IBS). Pinaverium bromide (pinaverium) has antispasmodic effects on gastrointestinal smooth muscle and can relieve major IBS symptoms, but an up-to-date meta-analysis comparing the efficacy […]

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Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases

Diagnosis, Evaluation, and Management of Ascites, Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome: 2021 Practice Guidance by the American Association for the Study of Liver Diseases Purpose and Scope of the Guidance This is a comprehensive guidance on the diagnosis, evaluation, and management of ascites and hepatorenal syndrome (HRS) in patients with chronic liver disease from […]

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Are Fourth-Year Medical Students as Prepared to Manage Unstable Patients as They Are to Manage Stable Patients?

Are Fourth-Year Medical Students as Prepared to Manage Unstable Patients as They Are to Manage Stable Patients? Abstract Purpose To evaluate the fourth-year medical student’s assessment and management of an unstable patient. Method The authors compared the performance of fourth-year medical students in a clinical performance examination (CPX) across a spectrum of simulated stable conditions […]

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The relation of 12 lead ECG to the cardiac anatomy: The normal CineECG

The relation of 12 lead ECG to the cardiac anatomy: The normal CineECG Background The interpretation of the 12‑lead ECG is notoriously difficult and requires experts to distinguish normal from abnormal ECG waveforms. ECG waveforms depend on body build and electrode positions, both often different in males and females. To relate the ECG waveforms to cardiac anatomical […]

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