Acute water intoxication in an adult man: ‘dental hyponatraemia’ revisited ABSTRACT The differential diagnosis of hyponatraemia is notoriously wide. However, only a minority is acute, ie develops in less than 48 hours. We describe an unusual cause of water intoxication due to toothache. A 30-year-old man with no medical history of note presented in an […]
The Monro-Kellie Doctrine: A Review and Call for Revision Abstract SUMMARY: The Monro-Kellie doctrine is a well-accepted principle of intracranial hemodynamics. It has undergone few consequential revisions since it was established. Its principle is straightforward: The combined volume of neuronal tissue, blood, and CSF is constant. To maintain homeostatic intracranial pressure, any increase or decrease in […]
Obstetric management of the most common autoimmune diseases: A narrative review Abstract Historically, women with an autoimmune disease (AD) could not get pregnant due to infertility frequently linked to the medical condition or because the pregnancy was contraindicated, as it could harm the mother and the future child. Sometimes, pregnancy was contraindicated because the medication […]
POCUS in dyspnea, nontraumatic hypotension, and shock; a systematic review of existing evidence Highlights Diagnostic accuracy of point-of-care ultrasound (POCUS) in patients with dyspnea, non-traumatic hypotension, and shock is higher when compared to not using POCUS in the initial workup.POCUS narrows the differential diagnoses and speeds up in time to diagnosis, where chest X-ray needs […]
Stroke and Emerging Blood Biomarkers: A Clinical Prospective Abstract Stroke constitutes the primary source of adult functional disability, exhibiting a paramount socioeconomic burden. Thus, it is of great importance that the prediction of stroke outcome be both prompt and accurate. Although modern neuroimaging and neurophysiological techniques are accessible, easily available blood biomarkers reflecting underlying stroke-related […]
Peritoneal Dialysis Prescription and Adequacy in Clinical Practice: Core Curriculum 2023 As the global prevalence of peritoneal dialysis (PD) continues to grow, practitioners must be equipped with prescribing strategies that focus on the needs and preferences of patients. PD is an effective form of kidney replacement therapy that offers numerous benefits to patients, including more […]
Diabetes management in chronic kidney disease: a consensus report by the American Diabetes Association (ADA) and Kidney Disease: Improving Global Outcomes (KDIGO) People with diabetes and chronic kidney disease (CKD) are at high risk for kidney failure, atherosclerotic cardiovascular disease, heart failure, and premature mortality. Recent clinical trials support new approaches to treat diabetes and CKD. […]
Treatments in Ischemic Stroke: Current and Future Abstract Background and Aim: Despite progress made over the last 30 years, stroke is still a leading cause of disability and mortality; likewise, its burden is expected to increase over the next decades, due to population growth and aging. The development of drugs with better safety-efficacy profiles as well […]
2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association Antecedentes y objetivo La hemorragia intracerebral (ICH) continúa siendo una forma mortal de accidente cerebrovascular; La mortalidad a los 90 días oscila entre el 15 % y el 40 %. Debido al aumento de la edad […]
The management of acute and chronic hyponatraemia Abstract Hyponatraemia is the most common electrolyte abnormality encountered in clinical practice; despite this, the work-up and management of hyponatraemia remain suboptimal and varies among different specialist groups. The majority of data comparing hyponatraemia treatments have been observational, up until recently. The past two years have seen the […]